Feipei Lai
Department of Computer Science & Information Engineering
and the Department of Electrical Engineering at National Taiwan University.
Next Generation Healthcare Information
System to support Precision Medicine
Abstract
In this talk, I will disclose how National Taiwan University Hospital (NTUH) has been building up the gene-related information infrastructure for precision medicine gradually since 2016. Precision medicine, an emerging approach for disease prevention and treatment that takes into account people’s individual variations in genes, environment, and lifestyle. We have built a gene-disease mutation viewer tool, called Mviewer, which can analyze the SNVs data with various annotations from different genome databases, as our preprocessing tools to decrease the numbers of candidate SNVs. Then, in this research, we describe a novel tool based on GeneReviews, Online Mendelian Inheritance in Man (OMIM) and biomedical literatures (PubMed) to rank SNVs from MViewer as well as the keywords automatically extracted from electronic medical records (EMRs) to get the most viable disease-causing candidates.
Autobibliography
Feipei Lai received a B.S.E.E. degree from National Taiwan University in 1980, and M.S. and Ph.D. degrees in computer science from the University of Illinois at Urbana-Champaign in 1984 and 1987, respectively.
He is a professor in the Graduate Institute of Biomedical Electronics and Bioinformatics, the Graduate Institute of Medical Device and Imaging, the Graduate Institute of Health Policy and Management, the Department of Computer Science & Information Engineering and the Department of Electrical Engineering at National Taiwan University. He serves as secretary in medical affairs, National Taiwan University Hospital. He was a vice superintendent of National Taiwan University Hospital. He was the chairman of Taiwan Network Information Center. He was a visiting professor in the Department of Computer Science and Engineering at the University of Minnesota, Minneapolis, USA. He was also a guest Professor at University of Dortmund, Germany and a visiting senior computer system engineer in the Center for Supercomputing Research and Development at the University of Illinois at Urbana-Champaign. His current research interest is Medical Informatics.
Prof. Lai is one of the founders of the Institute of Information & Computing Machinery and served as the President during 2009/7-2013/7. He is also a member of Phi Kappa Phi, Phi Tau Phi, Chinese Institute of Engineers, Chinese Institute of Electrical Engineers. Prof. Lai was the chairman of Taiwan Internet Content Rating Foundation. He received the Taiwan Fuji Xerox Research Award in 1991, K-T Li Breakthrough Award in 2008, IBM Faculty Award, NTU Distinguished Service Award in 2009, Taiwan 2010 IT Distinguished Professionals and 2013 Telehealthcare Distinguished Contribution Award.